Kazuichi Sakamoto

We have developed a new bioassay system to find and evaluate natural bioactive compounds (e.g. phytochemicals, plant extracts, fermented foods, and animal tissues) that influence health and aging; this novel bioassay system uses nematodes to characterize the bioactivity of natural substances. Because of its biological characteristics (easy culture, short lifespan, and availability of mutants), the nematode is a suitable and well-characterized model for investigating the physiology and mechanisms of human aging and disease. We are using this animal to screen for biomaterials with potential benefits for human health.

To promote health (prevention and amelioration of lifestyle-related diseases) and youth (anti-aging and vitality), we are searching for natural bioactive compounds. We are scientifically evaluating the bioactivity of these substances and developing novel bioactive materials. We are also conducting applied studies to develop functional foods, functional feeds, cosmetics, and medicines.

Phytochemicals such as catechin from tea, resveratrol from red grapes, and hydroxytyrosol from olives are famous bioactive compounds that can act against aging and help protect against lifestyle-related diseases. We are using these materials in functional foods, cosmetics, medicines, and other materials to promote health and slow aging.